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The End Up
Located in the hipster haven that is SOMA (South of Market Area), the End Up is everything that you would expect from a San Francisco dance club.  It's got a dance floor for those that gotta dance and a fireplace lounge for those that enjoy people watching.  If the dance floor gets too hot there's an open back patio to cool you off.  Like so many SF nightclubs the music and the clientele depend greatly on the day of the week. It's a good idea to call ahead.
401 6th Street Tel 415.357.0827

Simply referring to 1015 as a dance club is a lot like thinking of the Golden Gate as just a bridge. 1015 has the largest dance floor and the longest lines to the front door. Once last call is heard in San Francisco, hundreds flock to the already crowded 1015.  Waiting in line seems to be half the fun as patrons and passersby have the opportunity to see the latest trends in club wear.  Though law enforcement and some local residents would enjoy seeing the club shut down, the infamy only seems to add to the experience.
1015 Folsom Street Tel 415.431.1200

Elbo Room
Located in a hip and funky part of the Mission District, the Elbo Room provides two floors of entertainment.  The main bar and lounge are located on the first floor with the dance floor and stage upstairs. On a weeknight one can seek refuge from the crowd by sticking to the first floor, but on weekends the whole place is packed. The dance floor is usually worth braving with a variety of local artists playing jazz, funk, soul, Afro Cuban, or hip hop on a regular basis.
647 Valencia Street Tel 415.552.7788

The Red Room
This Theatre District cocktail lounge is aptly named.  Almost everything from the furniture to the lighting is red.  The noteworthy exceptions are the variety of colorful cocktails that make up the drink menu. Despite being small and uniformly crimson, the Red Room has a comfortable lounge character.
827 Sutter Street Tel 415.346.7666

The Blue Bar
Good, solid jazz in the Blue Bar is complimented by good, solid fare in the restaurant above.  The live jazz is definitely worth the small cover charge. One of the best features of the Blue Bar is that the restaurant above is open long past midnight.  Besides jazz, the Blue Bar is known to feature spoken-word poetry in the San Francisco tradition.
501 Broadway Tel 415.981.2233

Cafe Du Nord
Located on the site of a former speakeasy, Cafe Du Nord combines the decadent charm of the Prohibition era with some tasty eats.  Cafe Du Nord is a good place to sip your martini while listening to live jazz after you've had a big place of linguine for dinner.  The Cafe features jazz on the weekends, but on other nights you'll hear salsa, swing, or maybe even rock and roll.
2170 Market Street Tel 415.861.5016

Magnolia Pub and Brewery
Located in the Haight, the Magnolia Pub and Brewery serves up a variety of hand-crafted beers brewed on the sight.  The Magnolia Pub and Brewery usually has around a dozen of their own brews to serve, as well as guest beers from other local breweries.  The pub also serves food that is above average for bar fare.  Situated in a century-old Victorian, the pub has combined the woodwork and flooring of its past incarnation as a drugstore with whimsical murals and other modern decor.
1398 Haight Street Tel 415.864.PINT

Maritime Hall
Rock, Metal, Punk, Rap, Dance, Country, and all other sorts of musical acts have played at the Maritime Hall.  Despite it's capacity of over 1,500 the Maritime Hall does sell out on occasion. Calling ahead or visiting the web site for schedule and ticket information is highly recommended.
450 Harrison Street Tel 415.974.0634